Conformational properties of N',N'-dimethylamides of N-acetyldehydroalanine and N-acetyl-(Z)-dehydrophenylalanine.

نویسندگان

  • D Siodłak
  • M A Broda
  • B Rzeszotarska
  • A E Kozioł
  • I Dybała
چکیده

Conformational preferences of Ac-deltaAla-NMe2 and Ac-(Z)-deltaPhe-NMe2 were studied and compared with those of their monomethyl counterparts as well as with those of their saturated analogues. X-Ray data and energy calculations revealed a highly conservative conformation of the dehydro dimethylamides, which is located in a high-energy region of the Ramachandran map.

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عنوان ژورنال:
  • Acta biochimica Polonica

دوره 48 4  شماره 

صفحات  -

تاریخ انتشار 2001